Discovery may help unlock infertility in older women

Australian researchers may have found the key to unlocking the mystery of infertility, miscarriage and birth defects in older women over the age of 37.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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Publication date: Available online 12 June 2018 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Li Jie, Deng Li, Chen Yang, Zhang Haiying This systematic review aimed to compare the clinical efficacy of tamoxifen with that of clomiphene citrate (CC) in anovulatory patients. The PubMed, EMBASE, and CNKI databases were searched up to October 2016 for literature comparing tamoxifen with CC in anovulatory women. The pooled risk ratios (RR) or standardized mean differences (SMD) with 95% confidence intervals (CIs) were subjected to statistical analysis. Twelve studies involving 1302 p...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
A newly discovered sperm structure may play a role in infertility, miscarriages and birth defects, and could lead to new diagnostics and therapeutic methods.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
While infertility may be a problem affecting nearly 7.3 million women in the United States between the ages of 15-44, it is a topic that women often don’t discuss. Rather, they suffer from the emotional pain that accompanies hormone injections, multiple procedures, and sometimes miscarriage. How is it best to treat this vulnerable population that rarely gets the attention it deserves? The answer lies in a team approach to medicine. According to Dr. Michael Jacobs, reproductive endocrinologist and infertility expert, who is director of Fertility and IVF Center of Miami, “The best way to treat couples challenged ...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions OB/GYN Source Type: blogs
CONCLUSION: Grief and depressive symptoms is reduced over time while emotional experiences such as isolation, loss of baby and a devastating event persist for longer time than four months. Lack of previous children, previous miscarriage and infertility diagnosis could increase negative emotional experiences after miscarriage, this was especially pronounced for grief reaction. The questionnaires could be used both clinically and in research to understand the emotional experiences after miscarriage. PMID: 29864578 [PubMed - as supplied by publisher]
Source: Midwifery - Category: Midwifery Authors: Tags: Midwifery Source Type: research
In conclusion, the results of this study indicate that FXR1 is a novel COX-2 regulatory factor. PMID: 29852926 [PubMed - as supplied by publisher]
Source: Reproduction, Fertility, and Development - Category: Reproduction Medicine Authors: Tags: Reprod Fertil Dev Source Type: research
AbstractEvidence on the treatment of euthyroid infertile women and thyroid autoimmunity with thyroid hormone is scare, and therefore the recent study by Wang et al. is a welcome addition to it. Based on their results, thyroid hormone seems not to be indicated to decrease the miscarriage rate in that particular group of infertile women. This comment is meant to put the study results into perspective with the available evidence and the current guidelines, and to highlight its strengths and weaknesses.
Source: Thyroid Research - Category: Endocrinology Source Type: research
Conclusion(s) Letrozole has good effect on endometrial thickness more than Clomid or Clomid plus estradiol when used in women with unexplained infertility with statistically significant difference, but there was no significant difference regarding pregnancy and abortion rate with slight increase toward Letrozole.
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
This study investigated the relationship between the vitamin D [25(OH)D] level in individual follicles and oocyte developmental competence.MethodsA prospective cohort study in a private infertility center. Infertile women (N = 198) scheduled for intracytoplasmic sperm injection (ICSI) and a single embryo transfer (SET) provided serum samples and 322 follicular fluid (FF) specimens, each from a single follicle on the day of oocyte retrieval.ResultsFFs corresponding to successfully fertilized oocytes (following ICSI) contained significantly lower 25(OH)D level compared with those that were not fertilized (28.4 ...
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
Recurrent pregnancy loss ( repeated miscarriages or habitual abortions) is one of the most frustrating problems in medicine. It is hard for patients , because getting pregnant , and then losing the baby again and again is traumatic. It's bad for doctors, because patients have so many questions , and we don't have any answers ! The truth is that our tests are not very good, and there is little we can do to make n accurate a diagnosis. This is why, in about 80% of patients with recurrent pregnancy loss , inspite of extensive testing, we will not be able to find an underlying cause.Based on experience over many years, the one...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Tags: IVF miscarriage recurrent abortions recurrent miscarriage recurrent pregnancy loss Source Type: blogs
This study was descriptive and retrospective. Wider implications These results are consistent with those in the literature. Hysteroscopic enlargement metroplasty is now a well-established technique with few complications but which should nevertheless be reserved for symptomatic patients.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
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