Hypertension: Hypertension in pregnancy: a risk factor for the whole family?

Nature Reviews Nephrology 13, 326 (2017). doi:10.1038/nrneph.2017.54 Authors: Grace Z. Yu &Paul Leeson Hypertension in pregnancy is a known risk factor for increased cardiovascular risk for both the mother and her offspring. New findings suggest the offspring of normotensive pregnancies should also be considered at risk of high blood pressure if their mother has had hypertension in other pregnancies.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: News and Views Source Type: research

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ConclusionACUTE ABDOMEN sonographic approach in acute abdomen can play an important role in ruling out critical diagnosis, and can guide emergency physician or any critical care physician in patient management.
Source: Critical Ultrasound Journal - Category: Radiology Source Type: research
In this study we were interested in examining the number of patients developing preeclampsia with severe features at term. We also investigated whether factors at admission might be predictive of disease progression.We performed a retrospective cohort study at a tertiary obstetric hospital in Melbourne, Australia from 2015 to 2017. There were 124 participants presenting with preeclampsia at term and included in our study. After admission, 44.4% progressed to preeclampsia with severe features. Disease features at admission associated with disease progression were chronic hypertension, elevated systolic blood pressure, reduc...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
ConclusionThe yearly number of publications on pre-eclampsia has substantially increased, with a stable number of high-level study types and publications from high-impact journals. The reporting quality and usefulness of RCTs relating to pre-eclampsia have improved over time.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Conclusion: In healthy pregnancy, we reported CIMT was related to BMI and maternal age but not parity or gestational age. PMID: 31535936 [PubMed - as supplied by publisher]
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research
Conclusions: Mature ovarian teratoma, uterine fibroids and pregestational hypothyroidism may also contribute to the incidence of preeclampsia. PMID: 31530202 [PubMed - as supplied by publisher]
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research
Objectives: Either maternal gestational diabetes mellitus (GDM) or hypertensive disorder of pregnancy (HDP) is associated with an increased risk of obesity in the offspring. However, their joint associations with obesity in offspring remain unclear. We investigated the joint associations of maternal GDM and HDP with childhood overweight in offspring.Methods: We performed a large study in 1967 mother-child pairs. Maternal GDM was diagnosed according to the 1999 World Health Organization (WHO) criteria. HDP was defined as self-reported doctor-diagnosed hypertension or treatment of hypertension (including gestational hyperten...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Publication date: October 2019Source: Pregnancy Hypertension, Volume 18Author(s): Sandra S. Reyes-Aguilar, Irais Poblete-Naredo, Yury Rodríguez-Yáñez, Rogelio O. Corona-Núñez, Christian D. Ortiz-Robles, Emma S. Calderón-Aranda, Arnulfo AlboresAbstractThe impact of pregnancy hypertension in the offspring endothelia remains unknown. We evaluated the transcriptional expression of four genes that participate in the process of endothelial dysfunction using umbilical vein endothelial cell cultures (HUVEC) from healthy pregnant women (PW) and those with hypertensive disorders (HD). The cy...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
In this study, we investigated whether parental hypertension induces autonomic dysfunction in male adult offspring, and the H2S mechanism underlying this autonomic dysfunction. 2-kidney-1-clip method was employed to induce parental hypertension during pregnancy and lactation in rats. Basal blood pressure (BP) and autonomic function of male offspring in adulthood was evaluated. Additionally, either maternal hypertensive dams or their male offspring after weaning were treated with H2S to determine improving effects of H2S on autonomic dysfunction. The BP was significantly increased in male offspring of renovascular hypertens...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Hypertension is a common clinical complication in pregnancy, representing possible short-term and long-term risks of complications for both mothers and babies. Even if in a majority of cases hypertension is essential, possible secondary causes, which can be related to endocrine disorders, must be detected and correctly managed. This review focuses on the evaluation and the management of primary hyperaldosteronism, Cushing syndrome, and pheochromocytoma in pregnancy.
Source: Endocrinology and Metabolism Clinics of North America - Category: Endocrinology Authors: Source Type: research
Abstract BACKGROUND: The hypertensive disorders of pregnancy include pre-eclampsia, gestational hypertension, chronic hypertension, and undefined hypertension. Pre-eclampsia is considerably more prevalent in low-income than in high-income countries. One possible explanation for this discrepancy is dietary differences, particularly calcium deficiency. Calcium supplementation in the second half of pregnancy reduces the serious consequences of pre-eclampsia, but has limited effect on the overall risk of pre-eclampsia. It is important to establish whether calcium supplementation before, and in early pregnancy (before ...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
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