Diabetes: Renal responses to SGLT2 blockade

Nature Reviews Nephrology 13, 320 (2017). doi:10.1038/nrneph.2017.55 Author: Andrea Aguilar Inhibition of the sodium–glucose cotransporter 2 (SLGT2) efficiently controls glycaemia in patients with type 2 diabetes mellitus (T2DM) but it can also induce ketoacidosis. In a new study, Ele Ferrannini and colleagues show that the hyperketonaemia induced by SGLT2 blockade results from enhanced ketogenesis and
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research