Favorable long-term outcomes of isolated liver transplantation in a child with atypical hemolytic uremic syndrome caused by a novel complement factor H mutation .

We describe a case of neonatal onset aHUS caused by a novel mutation of CFH and treated with an isolated liver transplantation at the age of 24 months. Nearly 5 years post-transplant, the patient's health has been generally good without evidence of aHUS. This case report suggests that isolated liver transplantation in aHUS patients with CFH mutations and preserved eGFR could be a curative therapeutic option in contrast to long-term eculizumab therapy. . PMID: 28502324 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28502324?dopt=Abstract

Source: Clinical Nephrology - May 15, 2017 Category: Urology & Nephrology Authors: Cho H, Lee Y Tags: Clin Nephrol Source Type: research

Favorable long-term outcomes of isolated liver transplantation in a child with atypical hemolytic uremic syndrome caused by a novel complement factor H mutation .

Favorable long-term outcomes of isolated liver transplantation in a child with atypical hemolytic uremic syndrome caused by a novel complement factor H mutation .