The pharmacology and toxicology of the 'holy trinity' - Horsfall JT, Sprague JE.

Combining opioids with benzodiazepines and skeletal muscle relaxants ('The Holy Trinity') has been reported to potentiate the 'high'. Through unique interactions with colocalized μ-opioid and GABAA receptors, the combined use of these agents induces a syn...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news