Pharmacotherapy for diabetic peripheral neuropathy pain and quality of life: A systematic review

Conclusions: For reducing pain, duloxetine and venlafaxine, pregabalin and oxcarbazepine, tricyclic antidepressants, atypical opioids, and botulinum toxin were more effective than placebo. However, quality of life was poorly reported, studies were short-term, drugs had substantial dropout rates, and opioids have significant risks. Future studies should evaluate longer-term outcomes, use methods and measures recommended by pain organizations, and assess patients' quality of life.
Source: Neurology - Category: Neurology Authors: Tags: Quality of life, Peripheral neuropathy, Clinical trials Systematic review/meta analysis, All Pain, Neuropathic pain VIEWS & amp;amp; REVIEWS Source Type: research