Chronotherapy for hypertension in obstructive sleep apnoea (CHOSA): a randomised, double-blind, placebo-controlled crossover trial
Conclusions
Our findings support combining OSA treatment with morning administration of antihypertensives. Unlike in essential hypertension, our results do not support evening administration of antihypertensives, at least with perindopril. Further research is required before this strategy can be widely adopted into hypertension guidelines and clinical practice.
Trial registration number
ACTRN12611000216910, Results.
Source: Thorax - Category: Respiratory Medicine Authors: Serinel, Y., Yee, B. J., Grunstein, R. R., Wong, K. H., Cistulli, P. A., Arima, H., Phillips, C. L. Tags: Sleep Source Type: research
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