{alpha}-Tocopherol transfer protein mediates protective hypercapnia in murine ventilator-induced lung injury

Conclusions
Inspired CO2 upregulates αTTP which increases lung α-tocopherol levels and inhibits synthesis of a pathogenic chemoattractant.

Source: Thorax - May 15, 2017 Category: Respiratory Medicine Authors: Otulakowski, G., Engelberts, D., Arima, H., Hirate, H., Bayir, H., Post, M., Kavanagh, B. P. Tags: Respiratory physiology Source Type: research