A rare vascular complication in a patient with essential thrombocythaemia: spontaneous abdominal aortic dissection

A 27‐year‐old woman complained of waist and back pain. Abdominal computed tomography angiography showed abdominal aortic dissection, the blood count revealed a high platelet count of 1655 × 109/L. Negative for JAK2V617F, CALR and MPL mutations (i.e. triple‐negative), the patient was diagnosed as essential thrombocythaemia (ET) with abdominal aortic dissection and was treated with cytoreduction and antiplatelet drugs. Cases of abdominal aortic dissection in ET have not been previously reported. As such, we proposed a mechanism of abdominal aortic dissection caused by endothelial dysfunction and further emphasised appropriate management in ET with abdominal aortic dissection.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fimj.13407

Source: Internal Medicine Journal - May 14, 2017 Category: Internal Medicine Authors: Ye Chen, Xue Han, Fang Wang, Beibei Bai, Yingchun Wang Tags: Brief Communication Source Type: research