Isotretinoin in retrospect
When isotretinoin was introduced about 30 years ago, this oral retinoid was applauded as the answer for the treatment of acne. The side effects, for the most part, were recognized; however, indiscriminate use subsequently led to both government intervention and disappointment.
Source: Clinics in Dermatology - Category: Dermatology Authors: Ayse Serap Karadag, Lawrence Charles Parish, Wm Clark Lambert Tags: Comment and Controversy Source Type: research