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Motherhood, the Brain and Dementia: Changing Hormones Alter Risk

Throughout decades of study, hormone therapy (HT), often but not always the same as hormone replacement therapy (HRT), has been glorified and demonized in turn. The information that doctors receive has come from ongoing studies that seemed to offer over time radically conflicting results. A new study may add more confusion since this study has found that not only does HT given near menopause create changes in a woman’s brain, but motherhood itself creates changes. Read full article on how changing hormones can alter the risk of Alzheimer's: Support a caregiver or jump start discussion in support groups with real stories - for bulk orders of Minding Our Elders e-mail Carol  Related articles Coping with Criticism from the Loved One You Care For Proper Dementia Diagnosis May Require Referral to Specialist Male Caregivers Need Unique Support                Related StoriesIndividual Attention Important Benefit of Alzheimer's Eating StudyNighttime Snacks Stop Some Alzheimer's Wandering10 Tips to Ease Alzheimer's Sundowning 
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs

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Abstract Several lines of investigation have shown a protective role for estrogen in Alzheimer's disease through a number of biological actions. This review examines studies of the role of estrogen-related factors in age at onset and risk for Alzheimer's disease in women with Down syndrome, a population at high risk for early onset of dementia. The studies are consistent in showing that early age at menopause and that low levels of endogenous bioavailable estradiol in postmenopausal women with Down syndrome are associated with earlier age at onset and overall risk for dementia. Polymorphisms in genes associated wi...
Source: Free Radical Biology and Medicine - Category: Biology Authors: Tags: Free Radic Biol Med Source Type: research
Authors: Ruan Q, D'onofrio G, Wu T, Greco A, Sancarlo D, Yu Z Abstract The aim of the present study was to assess systematically gender differences in susceptibility to frailty and cognitive performance decline, and the underlying mechanisms. A systematic assessment was performed of the identified reviews of cohort, mechanistic and epidemiological studies. The selection criteria of the present study included: i) Sexual dimorphism of frailty, ii) sexual dimorphism of subjective memory decline (impairment) and atrophy of hippocampus during early life, iii) sexual dimorphism of late‑onset Alzheimer's ...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Good news, coffee lovers. A new study has uncovered a significant link between caffeine consumption in older women and a reduced risk of dementia. Although researchers have yet to establish a “cause and effect” between the two, they did find a strong relationship between higher caffeine consumption in women 65 and older and a lower risk of developing dementia or cognitive impairment. Specifically, those women who self-reported drinking more than 261 milligrams of caffeine per day ― or about two to three eight-ounce cups of coffee or five to six eight-ounce cups of black tea ― enjoyed a 36 percent decline in...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Initially, I found it very hard to accept that mum was living with dementia. I knew very little about the condition or what to expect, and frankly I found it terrifying.For some it seems elusive but as Alice Ashwell has explained in this two part interview with Tom and Karen Brenner, Alzheimer's care and dementia care gives to each of us the opportunity to live a meaningful and purposeful life.This is part two of an interview with Alice.Alzheimer's Care The Power of Purpose in Our LivesSubscribe to the Alzheimer's Reading RoomEmail:By Tom and Karen Brennerwith Alice AshwellAlzheimer's Reading Room4.How did your mother &rsq...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer's awareness alzheimer's care Alzheimer's Dementia dementia care dementia help for caregivers help with dementia care memory care nursing home searches related to dementia care Source Type: blogs
This study provides additional fuel to really bolster research efforts by us and others in geroscience, a field that seeks to understand relationships between the biology of aging and age-related diseases. Aging is the most important risk factor for common chronic conditions such as heart disease, Alzheimer's and cancer, which are likely to share pathways with aging and therefore interventions designed to slow biological aging processes may also delay the onset of disease and disability, thus expanding years of healthy and independent lives for our seniors." Longer-Lived Parents and Cardiovascular Outcomes ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Growing up a musically-obsessed child in the 80's, Daryl Hall was one of my biggest inspirations. A masterful, inventive songwriter with an ocean of soul, he set me on the path to being an artist, to never waste a word, and to sing because I mean it. With six number ones and five additional top ten hits throughout the 70's and 80's Daryl Hall and John Oates are the number one duo in music history. Still at the top of his game at 69 years old, Daryl has won legions of new fans with his hit MTV Live show Live From Daryl's House. In February of 2015, at my very sickest from chronic Lyme and Bartonella, after it was missed b...
Source: Science - The Huffington Post - Category: Science Source Type: news
Men traditionally spend more time in work - and this activity may leave their brains better able to resist damage, reducing the impact of dementia, University of Hertfordshire researchers theorised.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conclusion This study of 324 female twins from the UK found a positive association between leg extensor power and age-related cognitive activity. As it was a cohort study, it is not possible to say that increased muscular strength prevented decline in mental ability, as other related or unrelated factors could have played a part. That said, the researchers did try to account for many of these factors, such as: using twins to reduce potential genetic and early environmental confounding factors taking baseline cardiovascular risk factor profiles, as these are risk factors for dementia taking into account age and s...
Source: NHS News Feed - Category: Consumer Health News Tags: Lifestyle/exercise Neurology Older people Source Type: news
Abstract Age-related changes in reproductive hormone levels are a well-known risk factor for the development of cognitive dysfunction and dementia in women. We and others have shown an important contribution of gonadotropins in this process. Lowering serum gonadotropin levels is able to rescue cognitive function in Alzheimer's disease and menopause models, but whether this is time-dependent and the exact mechanism through which gonadotropins regulate cognitive function is unknown. We show that pharmacologically lowering serum levels of luteinizing hormone lead to cognitive improvement immediately after ovariectomy...
Source: Hormones and Behavior - Category: Endocrinology Authors: Tags: Horm Behav Source Type: research
WASHINGTON (AP) — Nearly two-thirds of Americans with Alzheimer’s disease are women, and now some scientists are questioning the long-held assumption that it’s just because they tend to live longer than men. What else may put woman at extra risk? Could it be genetics? Biological differences in how women age? Maybe even lifestyle factors? Finding out might affect treatments or preventive care. One worrisome hint is that research shows a notorious Alzheimer’s-related gene has a bigger impact on women than men. INCREASED RISK IN WOMEN “There are enough biological questions pointing to increased r...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Local News Alzheimer's Disease ApoE-4 Estrogen gene Women's Risk Source Type: news
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