Neuraxial anesthesia in a patient with Anti-N-methyl-D-aspartate receptor encephalitis in pregnancy: management for caesarean delivery and oophorectomy

Anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDARE) is a neurological disorder caused by production of antibodies to the NMDA receptor (NMDAR) and is usually associated with ovarian teratomas in women of child-bearing age. It is characterized by major psychiatric and neurologic symptoms, which may worsen with pregnancy. It often starts with a prodromal viral-like illness followed by predominantly psychiatric symptoms including agitation, paranoia, catatonia, and hallucinations. Neurologic symptoms including decreased consciousness, dyskinesia, seizures, autonomic dysfunction, central hypoventilation and dysthermia may develop.
Source: International Journal of Obstetric Anesthesia - Category: Anesthesiology Authors: Tags: Case report Source Type: research