Is rheumatoid arthritis associated with a declined immunogenicity of influenza vaccination? A systematic review and meta-analysis.

CONCLUSIONS: The immunogenicity was significantly different between RA patients and the healthy controls for H1N1 strain, but not for H3N2 or B strains. Adverse event rates were higher in RA patients. Adjuvant and special kinds of immunosuppressive biologics may play an important role in immunogenicity of inactivated influenza vaccines for RA patients. PMID: 28489423 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research