New Data Reinforce Benefits of TomoTherapy(R) Platform for Mainstream Radiation Therapy Treatment Indications

Multiple Studies Presented at ESTRO 36 Demonstrate System Improves Tumor Control withReduced Toxicities SUNNYVALE, Calif., May 11, 2017 -- (Healthcare Sales &Marketing Network) -- Accuray Incorporated (NASDAQ: ARAY) announced today that studies contin... Devices, Oncology Accuray, TomoTherapy, radiotherapy, IMRT
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news

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This study addresses the third one, also called the leaf sequencing problem, which arises for each chosen irradiation angle, given the optimized fluence map. It consists in defining a sequence of configurations of a device (called multileaf collimator) that correctly delivers radiation to the patient. A usual model for this problem is the decomposition of a matrix into a weighted sum of (0,1)-matrices, called segments, in which the ones in each row appear consecutively. Each (0,1)-matrix corresponds to a configuration of the device. The realization problem has three objectives. The first one is to minimize the sum of weigh...
Source: Medical and Biological Engineering and Computing - Category: Biomedical Engineering Source Type: research
OBJECTIVE: To analyze the pattern of local failure in patients with nasopharyngeal carcinoma (NPC) after intensity-modulated radiotherapy (IMRT) and find a more reasonable delineation of the clinical target volume (CTV).METHODS AND MATERIALS: A total of 212 patients with non-metastatic NPC who underwent IMRT were analyzed. Radiation therapy was run at a total dose of 66-74 Gy (2.0-2.2 Gy fractions). The follow-up of local recurrence and the recurrence-related features were analyzed for the original treatment situation. The failures were delimited as “in-field failure” if Vrecur within the 95% isodose curve (V95...
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors of the head and neck in Southeast Asia and southern China. Although the comprehensive treatment based on intensity-modulated radiation therapy improves outcomes, the five-year survival rate of NPC patients is low, and the recurrence remains high. Radiotherapy resistance is the main cause of poor prognosis in NPC patients. MicroRNAs (miRNAs) are a class of endogenous non-coding RNAs regulating various biological functions in eukaryotes. These miRNAs can regulate the development and progression of nasopharyngeal carcinoma by affecting the proliferation...
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
This study demonstrated that after the completion of 3-4 cycles of chemotherapy with a remission, concurrent chemoradiotherapy with oral etoposide and cisplatin improved survival compared with sequential chemoradiotherapy in LS-SCLC with bulky tumor. Identifier: NCT01745445.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
Radiation therapy remains an essential component of cancer therapy for millions of patients annually in the United States and globally. Radiation therapy involves the focal deposition of ionizing radiation (IR) to the tumor and surrounding at-risk tissue compartments such as regional lymph nodes. The most common treatment approaches include external beam radiation therapy (EBRT) using high-energy photons, electrons, or protons, as well as brachytherapy and radionuclide therapy. Significant technical advances in EBRT and diagnostic imaging over the past several decades have enabled more localized and precise dose deposition...
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Review Article Source Type: research
Target volume delineation has always been but has become increasingly challenging in radiation oncology given the ever more prevalent use of techniques such as 3D conformal radiation therapy and intensity-modulated radiation therapy (IMRT) that enable dose escalation while sparing adjacent normal tissue.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Short Communication Source Type: research
Conclusion: SRS/FRT remains a useful adjuvant for treatment of residual or recurrent ELSTs, where the risk of revision microsurgical resection is high.
Source: Otology and Neurotology - Category: ENT & OMF Tags: TUMORS OF THE EAR AND CRANIAL BASE Source Type: research
ConclusionsBased on a Markov microsimulation analysis, both AI-alone and APBI-alone are appropriate options for patients 70  years or older with early breast cancer with small cost differences noted. A prospective trial comparing the approaches is warranted.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
ConclusionAdjuvant hypofractionated prone breast IMRT has excellent locoregional control and minimal toxicity.
Source: Journal of Medical Imaging and Radiation Oncology - Category: Radiology Authors: Tags: Radiation Oncology —Original Article Source Type: research
Conclusion: This analysis uses TDABC to estimate the relative internal costs of various RT strategies associated with treating oligometastatic NSCLC. This methodology will become increasingly relevant to each organization in context of the anticipated mandate of alternative/bundled payment models for radiation oncology by the Centers for Medicare and Medicaid Services. PMID: 32529054 [PubMed]
Source: Clinical Lung Cancer - Category: Cancer & Oncology Authors: Tags: Clin Transl Radiat Oncol Source Type: research
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