ReKOMendacje Post ępowAnia w mukowiScydozie (cystic fibrosis; CF) dla lekarzy Podstawowej Opieki Zdrowotnej – KOMPAS CF – część 2

Publication date: Available online 10 May 2017 Source:Pediatria Polska Author(s): Dorota Sands, Katarzyna Walicka-Serzysko, Zbigniew Doniec, Agnieszka Mastalerz-Migas, Halina Batura-Gabryel, Władysław Pierzchała With the prolonged life, patients with cystic fibrosis require multi-specialty care including not only the treatment of the underlying disease but also its complications and associated diseases. Complications of bronchopulmonary disease, both infectious (fungal infections) and non-infectious (haemoptysis, pneumothorax, respiratory failure) are often a direct threat to life and require rapid identification and proper management. Dietary treatment aims to prevent malnutrition and disturbances of water-electrolyte management with cystic fibrosis characterized by metabolic alkalosis with hyponatremia and hypochloraemia (pseudo Bartter syndrome). At every stage of the disease, there are gastrointestinal complications that require special treatment and appropriate treatment: from meconium ileus, through distal intestinal obstruction syndrome, reflux disease, pancreatitis, and cystic fibrosis related diabetes or liver diseases. Patients with chronic inflammation and polyps of paranasal sinuses required laryngological care. The end of life is a time to choose whether to continue palliative treatment or to qualify for lung transplantation.
Source: Pediatria Polska - Category: Pediatrics Source Type: research

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Authors: Papachristou SG, Iosifidis E, Sipsas NV, Gamaletsou MN, Walsh TJ, Roilides E Abstract Introduction: Osteoarticular fungal infections (OAFIs) complicate the clinical course of high-risk patients, including immunosuppressed individuals. Their management, however, despite being intricate, is governed by evidence arising from sub-optimal quality research, such as case series. Guidelines are scarce and when present result in recommendations based on low quality evidence. Furthermore, the differences between the management of immunocompromised and immunocompetent patients are not distinct. This is a narrative re...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
Publication date: Available online 27 March 2020Source: European Journal of Surgical OncologyAuthor(s): Willemijn Y. van der Plas, Stan Benjamens, Schelto Kruijff
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
We present an up-to-date systematic review of the current literature regarding the safety in artificial and natural sweeteners use as a means of weight loss or diabetes control.Expert opinion: Natural sweeteners have not been associated directly with NAFLD, and on the contrary, some, such as stevia, and trehalose, may have a protective effect. Rare sugars and polyols can be used safely and have significant benefits that include anti-oxidant effect and optimal glycemic control. Artificial sweeteners, due to their effect on NAFLD development and insulin resistance, are not indicated in patients with obesity or diabetes. Furt...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Conclusion: Serum GGT level was a significant predictor of subsequent risk of diabetes mellitus, which increased by 4% for every 1 IU/L increase in GGT when GGT was less than 24 IU/L. PMID: 32215009 [PubMed]
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
In this study, we aimed to evaluate the influence of insulin production on immune system after the onset of diabetes, and we showed that the duration of honeymoon period could be related to the onset of other autoimmune conditions. For this retrospective study, 159 children aged between 11 and 18 years with type 1 DM were eligible. They have been diagnosed diabetes at least 10 years ago and use exogenous insulin. Our results showed that younger age at the onset of Type 1 DM in children, predicts Celiac Disease. Female sex and low HCO3 levels at the onset of DM had a high predictive value on patients who did not experience ...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
In conclusion, the decreased numbers of VZV-specific CD8+T-cells during the acute phase and VZV-specific CD4+T-cells during the convalescent phase of disease may account for severe varicella in immunocompromised children. PMID: 32213753 [PubMed - in process]
Source: The Tohoku Journal of Experimental Medicine - Category: Research Authors: Tags: Tohoku J Exp Med Source Type: research
Publication date: Available online 27 March 2020Source: Molecular MetabolismAuthor(s): Lucia Russo, Lindsey Muir, Lynn Geletka, Jennifer Delproposto, Nicki Baker, Carmen Flesher, Robert O’Rourke, Carey N. Lumeng
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Publication date: Available online 27 March 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Roberto Laza-Cagigas, Shirley Chan, Daniel Sumner, Tarannum Rampal
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: March–April 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &Reviews, Volume 14, Issue 2Author(s):
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Authors: Wang LP, Geng JN, Sun B, Sun CB, Shi Y, Yu XY Abstract Purpose: The current study aims to examine the effects of advanced glycation end products (AGEs) on the microRNA (miRNA) expression profile in the kidney tissues of rats. Methods: Wistar rats were randomly divided into three equal experiment groups: the AGE group, the RSA group, and the control group. The rats in the AGE group and the RSA group were administered with advanced glycation end products (AGEs) and rat serum albumin (RSA) via the tail vein, respectively, whereas the control group received PBS. Total RNA was prepared from the rat kidney t...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
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