Bilateral Compressive Optic Neuropathy from Renal Osteodystrophy Caused by Branchio-oto-renal Syndrome Stabilised After Parathyroidectomy

Source: Neuro-Ophthalmology - Category: Opthalmology Authors: Source Type: research

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ConclusionHypocalcemia after total thyroidectomy is a complex, probably multifactorial issue. Systematic parathyroid gland identification is not recommended due to the increased risk of gland lesion, mainly by devascularization. Incidental parathyroidectomy may induce hypocalcemia at 1 month postoperatively (statistically “suggestive” association).
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
AbstractParathyroid surgery is frequently performed after at least two preoperative localisation studies, in addition to the use of intraoperative ioPTH. The key to performing a successful parathyroidectomy is reliant on the surgeon having an outstanding knowledge of parathyroid embryology and anatomy. With this, it is possible to undertake surgery with a simple neck ultrasound and without more expensive pre- and intraoperative localisation studies.
Source: World Journal of Surgery - Category: Surgery Source Type: research
This study evaluates parathyroidectomy outcomes in elderly patients.MethodsPrimary hyperparathyroidism patients having parathyroidectomy as listed in the 2005 –2017 ACS-NSQIP database were separated by age: ≤60, 61–79 and ≥80. Outcomes included complications, 30-day mortality, return to the OR, operating times, and hospital length of stay (LOS). Multivariable logistic regression was used to compare patients 61–79 and ≥80 to those ≤60. Patien ts ≤60 and ≥80 were propensity score matched using gender, race, BMI, smoking status, steroid use, modified frailty index (mFI), ASA class, procedur...
Source: World Journal of Surgery - Category: Surgery Source Type: research
ConclusionsUS sensitivity improves when there is no concomitant thyroid pathology. MIBI-PS sensitivity improves when the gland weight is greater than 600 mg.ResumenIntroducciónUna correcta localización preoperatoria del adenoma es clave en el tratamiento del hiperparatiroidismo primario (HPTP) mediante paratiroidectomía selectiva. Aunque existen múltiples técnicas de imagen, no siempre consiguen localizar correctamente la/s glándula/s patológica/s. El objetivo es estudiar los factores que puedan influir en la sensibilidad y la concordancia de la ecografía y la ...
Source: Cirugia Espanola - Category: Surgery Source Type: research
Authors: Ma H, Ouyang C, Huang Y, Xing C, Cheng C, Liu W, Yuan D, Zeng M, Yu X, Ren H, Yuan Y, Zhang L, Xu F, Cui Y, Ren W, Huang H, Qian H, Fan B, Wang N Abstract Purpose: Microwave ablation (MWA) is feasible for severe renal secondary hyperparathyroidism (SHPT) and primary hyperparathyroidism (PHPT) patients ineligible for parathyroidectomy (PTX). Here we compared the clinical manifestations and characteristics of parathyroid glands in these two groups, and summarized the techniques, safety and efficacy of MWA.Methods: Baseline clinical characteristics, ablation-related techniques, adverse events/complications, a...
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
Authors: Torresan F, Iacobone M Abstract Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is an autosomal dominant disorder characterized by parathyroid tumors in association with fibro-osseous jaw tumors and uterine and renal lesions. HPT-JT syndrome is caused by germline mutations of the cell division cycle 73 (CDC73) gene that encodes the parafibromin, a 531-amino acid protein with antiproliferative activity. Primary hyperparathyroidism is the main finding of HPT-JT syndrome, usually caused by a single-gland parathyroid involvement (80% of cases), at variance with other variants of hereditary hyperparathyroidism,...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
ConclusionNeonatal severe primary hyperparathyroidism is a life-threatening condition. Early surgery is life-saving in cases in whom medical therapy fails to control the disease.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
CONCLUSION: Four-dimensional magnetic resonance imaging had high accuracy with fast dynamic imaging in detecting parathyroid adenomas. When the first-line imaging methods were negative or inconclusive, four-dimensional magnetic resonance imaging should be considered primarily since it is cost effective in Turkey and emits no radiation. PMID: 31918555 [PubMed - as supplied by publisher]
Source: Annals of the Royal College of Surgeons of England - Category: Surgery Authors: Tags: Ann R Coll Surg Engl Source Type: research
Conclusion: Results from our study show that most of the patients with renal hyperparathyroidism were symptomatic preoperatively and the most common clinical presentations were bone pain and muscle weakness. The significant predictor of early postoperative hypocalcemia after total parathyroidectomy was the preoperative alkaline phosphatase levels. PMID: 31909044 [PubMed]
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
ConclusionIn this multi-institutional series of PHPT in children and adolescents, the majority were sporadic PHPT and were due to a single adenoma. We observed a high incidence of ectopic parathyroid adenomas, most commonly intrathymic. Given the high risk for ectopic adenoma in pediatric patients, parathyroid surgery in children and adolescents should be performed by experienced surgeons.
Source: World Journal of Surgery - Category: Surgery Source Type: research
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