Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice Stroke

ConclusionsWe conclude that brain ischemia induces the formation of β‐hydroxybutyrate (ketogenesis) in the liver and the consumption of β‐hydroxybutyrate in the brain. This effect seems to be mediated by β‐adrenergic receptors.
Source: JAHA:Journal of the American Heart Association - Category: Cardiology Authors: Tags: Ischemia, Metabolism, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Research Source Type: research

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Rejuvenation Research, Ahead of Print.
Source: Rejuvenation Research - Category: Genetics & Stem Cells Authors: Source Type: research
Condition:   Ischemic Stroke Intervention:   Sponsor:   University Hospital Inselspital, Berne Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Acute Ischemic Stroke Patients Intervention:   Other: observational study Sponsor:   Ain Shams University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 11 December 2019Source: Journal of Clinical NeuroscienceAuthor(s): Alex Buoite Stella, Marina Gaio, Giovanni Furlanis, Mariana Ridolfi, Miloš Ajčević, Arianna Sartori, Paola Caruso, Shawnda A. Morrison, Marcello Naccarato, Paolo ManganottiAbstractHypohydration has been suggested increasing the risk of vascular diseases, and it is associated with poor prognosis and worse functional outcome in stroke. Most studies have used blood parameters to determine patients’ hydration status. The aim of this study was to measure urine osmolality (uOsm) and its influence on stroke severit...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Conditions:   Ischemic Stroke;   Cancer Intervention:   Other: Risk factors Sponsor:   Mansoura University Hospital Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: It was feasible to randomize AIS patients receiving either general anesthesia or conscious sedation for EVT.
Source: Journal of Neurosurgical Anesthesiology - Category: Anesthesiology Tags: Clinical Investigations Source Type: research
Abstract Worldwide, millions of individuals suffer an ischemic stroke each year, causing major disability, especially in the elderly, where stroke is the number one cause of disability. However, to date, no effective therapy exists that targets the functional recovery after stroke. After necrosis, neuroinflammation is a common feature of the acute stroke and a major obstacle to tissue restoration. In the lesioned area, the dying neurons release chemotactic signals, such as fractalkine/CX3CL1, which evoke "eat-me" signals that are recognized by microglia expressing complement C3a receptor (C3aR), resultin...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
Publication date: Available online 9 December 2019Source: NeuroImage: ClinicalAuthor(s): Yunzhe Xue, Fadi G. Farhat, Olga Boukrina, A.M. Barrett, Jeffrey R. Binder, Usman W. Roshan, William W. GravesAbstractAutomatic identification of brain lesions from magnetic resonance imaging (MRI) scans of stroke survivors would be a useful aid in patient diagnosis and treatment planning. It would also greatly facilitate the study of brain-behavior relationships by eliminating the laborious step of having a human expert manually segment the lesion on each brain scan. We propose a multi-modal multi-path convolutional neural network sys...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
AbstractPurpose of reviewEndovascular thrombectomy (ET), the standard of treatment for emergent large vessel occlusion (ELVO) strokes, has been subject to rigorous efforts to further improve its usage and delivery for optimised patient outcomes. This review aims to provide an outline and discussion about the recently established and emerging recommendations regarding endovascular treatment of stroke.Recent findingsThe indications for ET have expanded continually, with perfusion imaging now enabling selection of patients presenting 6 –24 h after last-known-well, and improved device and operator proficiency allowi...
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research
Here we present a patient with oropharynx infection by Fusobacterium necrophorum (F. necrophorum) who developed arterial wall inflammation and longitudinal stenosis of the right internal carotid artery and right hemispheric ischemic stroke. To our knowledge, longitudinal stenosis caused by F. necrophorum in Lemierre's syndrome has not previously been described.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research
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