Pain Relievers Tied to Immediate Heart Risks

The risk of having a heart attack rises within the first week of starting Nsaids, though the absolute risk remains small.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Heart Aleve (Drug) Source Type: news

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Authors: Shao C, Wang J, Tian J, Tang YD Abstract In most developed countries, coronary artery disease (CAD), mostly caused by atherosclerosis of coronary arteries, is one of the primary causes of death. From 1990s to 2000s, mortality caused by acute MI declined up to 50%. The incidence of CAD is related with age, gender, economic, etc. Atherosclerosis contains some highly correlative processes such as lipid disturbances, thrombosis, inflammation, vascular smooth cell activation, remodeling, platelet activation, endothelial dysfunction, oxidative stress, altered matrix metabolism, and genetic factors. Risk factors ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Heart attack symptoms include chest pain, difficulty breathing, and an overwhelming feeling of anxiety. But you could also be at risk of a deadly myocardial infarction and heart disease if you have painful lumps on your feet - do your toes look like this?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Heart attack symptoms include chest pain, difficulty breathing, and an overwhelming feeling of anxiety. But you could also be at risk of a deadly myocardial infarction and heart disease if you have this subtle warning sign on your skin - do your arms or legs have these coloured patterns?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Coronavirus is a deadly infection that's already killed more than 1,200 people in the UK, and could easily be confused with flu symptoms. You could also be at risk of the virus if you've developed the same signs as a heart attack, including chest pain.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
RARITAN, NJ, March 28, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson today announced the VOYAGER PAD study met its primary efficacy and principal safety endpoints, demonstrating the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily) plus aspirin (100 mg once daily) was superior to aspirin alone in reducing the risk of major adverse limb and cardiovascular (CV) events by 15 percent in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization, with similar rates of TIMI[1] major bleeding. VOYAGER PAD is the only study to show a significant benefit...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Abstract Takotsubo syndrome (TTS), also known as stress cardiomyopathy, is a type of acute heart failure syndrome triggered by intense psychological or physiological stress. TTS typically manifests as acute chest pain, dyspnea or syncope that mimics an acute myocardial infarction but does not involve coronary artery obstruction. The current understanding of the pathogenesis of TTS suggests that sympathetic nervous system (SNS) activation plays a central role. Specifically, stress can activate the SNS and lead to the over-release of catecholamine, which have toxic effects on myocardial tissue when present at excess...
Source: Cardiology Research and Practice - Category: Cardiology Authors: Tags: Cardiol Res Pract Source Type: research
Stress caused by uncertainty can be paralyzing. The information we are getting about the coronavirus seems to be changing by the hour — creating unprecedented uncertainty. There is a good reason your nerves are jangle, or you are feeling unsettled or anxious. Uncertainty is perceived as unsafe and potentially painful. Whether the situation is predictably positive or predictably negative, your brain prefers something familiar to something unfamiliar. Under stress, our brains depend on instinct rather than rational thought because the part of the brain responsible for critical thinking is busy dealing with the psycholo...
Source: Embrace Your Heart Wellness Initiative - Category: Cardiology Authors: Tags: Stress Management uncertainty Source Type: blogs
While at work, one my partners showed me this ECG of a 50-something woman with abdominal pain associated with alcohol withdrawal and alcoholic ketoacidosis.  There was no reported chest pain or SOB.What do you think?I said it " looks like takotsubo.  Electrolytes might contribute.  Are they back yet? (they were not).  I do not think this is a coronary event. "He asked why.I responded: " bizarre T-waves, with T-wave inversion and extremely long QT.  The computer measures the QT at 506 ms, but it really is more like 560-580 ms, with a QTc of 600-620 ms.  This is not at all typical...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
CONCLUSIONS: The well-documented risk factors are age, history of diabetes mellitus and renal failure, multivessel coronary artery disease on angiography and time from pain onset to first medical contact. The less conventional risk predictors are total amount of contrast agent administered during invasive procedures and patient radiation exposure during the procedures. PMID: 32207699 [PubMed - as supplied by publisher]
Source: Kardiologia Polska - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research
RARITAN, N.J., March 20, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson announced today that it will unveil late-breaking data from its leading cardiovascular and metabolism portfolio during the virtual American College of Cardiology’s 69th Annual Scientific Session together with the World Congress of Cardiology (ACC.20/WCC) on March 28-30, 2020. Notably, four late-breaking abstracts for XARELTO® (rivaroxaban) will be presented, including data from the Phase 3 VOYAGER PAD study in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization.Click to ...
Source: Johnson and Johnson - Category: Pharmaceuticals Source Type: news
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