Listeria rhomboencephalomyelitis complicated by haemorrhagic transformation

Conclusions Concurrent Listeria myelitis with rhomboencephalitis has not been reported. Furthermore, the corresponding MRI hyperintensities demonstrated haemorrhagic transformation without abscess formation is a novel finding, likely secondary to bacterial invasion or localised necrotic inflammation of blood vessels leading to exudation of blood products. First line treatment of CNS Listeriosis is either ampicillin or benzylpenicillin with sulfamethoxazole/trimethoprim as second line treatment. Consideration of switching antibiotics in the event of inadequate clinical improvement can be trialled as Australian guidelines differ from international ones.
Source: Journal of Neurology, Neurosurgery and Psychiatry - Category: Neurosurgery Authors: Tags: Abstracts Source Type: research