Myasthenia gravis with an unusual pattern of weakness and positive igg anti gm1 antibody

Conclusions This case highlights the varied clinical presentation of NMJ disorder like myasthenia gravis. Whether the positive anti GM1 antibody in this case is a pathological antibody or if its presence is coincidental or an epiphenomenon is unclear. NMJ junction is rich in gangliosides and potential NMJ dysfunction may occur but clinical cases of myasthenia associated with antiGM1 antibodies has not been reported to our knowledge.

http://jnnp.bmj.com/cgi/content/short/88/5/e1-u?rss=1

Source: Journal of Neurology, Neurosurgery and Psychiatry - May 8, 2017 Category: Neurosurgery Authors: Ng, J. L., Hooi, W. F., Malhotra, A., Talman, P. Tags: Abstracts Source Type: research