Comparing magnetic resonance imaging brain atrophy measurement techniques in multiple sclerosis clinical practice: longitudinal assessment

Conclusions WBA measurements derived using the fully automated MSmetrix-long correlated strongly with the results using SIENA, however, measurements using SIENAX correlated weakly. Longitudinal registration-based techniques hold promise for use in MS clinical practice but are currently not validated at the individual patient level. Fully automated, easy-to-use platforms are likely to accelerate translation from the research setting into routine MS care, and subsequently warrant further investigation. Segmentation-based methods currently have measurement error rates that render them suboptimal for use in longitudinal assessment, especially at the individual level. Technical improvements and the development of reference populations may result in these techniques having a place in future MS patient care.
Source: Journal of Neurology, Neurosurgery and Psychiatry - Category: Neurosurgery Authors: Tags: Abstracts Source Type: research