Roles of NADPH oxidase and mitochondria in flow ‐induced vasodilation of human adipose arterioles: ROS induced ROS release in coronary artery disease

ConclusionsThese findings indicate that ROS produced by NADPH oxidase are an upstream component of the mitochondria‐dependent pathway contributing to flow‐dependent H2O2 generation and dilation in peripheral microvessels from patients with CAD. We conclude that in CAD, both mitochondria and NADPH oxidase contribute to FID through a redox mechanism in visceral arterioles.This article is protected by copyright. All rights reserved.
Source: Microcirculation - Category: Research Authors: Tags: Original Research Source Type: research