Influence of Pilocarpine and Timolol on Human Meibomian Gland Epithelial Cells
Conclusions: Our results support our hypothesis and demonstrate that these antiglaucoma drugs, pilocarpine and timolol, have direct effects on HMGECs that may influence their morphology, survival, and proliferative capacity.
This article reviews complications and adverse events of plaque brachytherapy, including scleral necrosis, strabismus, cataract, glaucoma, and retinopathies as well as management of these conditions. For practicing oncologists and ophthalmologists, these complications are important to understand, identify, and treat. Additionally, an understanding of common complications of brachytherapy should influence the decision of pursuing it as a treatment option. PMID: 31523242 [PubMed]
Condition: Glaucoma Intervention: Device: Micro-invasive Glaucoma Surgical Devices Sponsor: National University Hospital, Singapore Recruiting
Conclusions: In this AD cohort, patients with advanced glaucoma had lower serum levels of vitamin D compared with early glaucoma and normal subjects. PMID: 31523121 [PubMed - in process]
In this study, researchers studied 438,952 participants in the UK Biobank, who had a total of 24,980 major coronary events - defined as the first occurrence of non-fatal heart attack, ischaemic stroke, or death due to coronary heart disease. They used an approach called Mendelian randomisation, which uses naturally occurring genetic differences to randomly divide the participants into groups, mimicking the effects of running a clinical trial. People with genes associated with lower blood pressure, lower LDL cholesterol, and a combination of both were put into different groups, and compared against those without thes...
CONCLUSIONS: The present study indicated that the MAFs of ASB10 gene polymorphisms showed a large difference among various ethnic groups, and that ASB10 gene polymorphisms may not be associated with genetic susceptibility to NTG in a Korean cohort. PMID: 31522561 [PubMed - as supplied by publisher]
Publication date: Available online 12 September 2019Source: Journal of American Association for Pediatric Ophthalmology and StrabismusAuthor(s): Sanika Udyaver, Lauren A. Dalvin, Li-Anne S. Lim, Mehdi Mazloumi, Hatice T. Atalay, Chloe T.L. Khoo, Jerry A. Shields, Carol L. ShieldsAbstractPurposeTo evaluate the effects of clinical features associated with enucleation in eyes with Coats disease.MethodsThe medical records of all patients with Coats disease at the Ocular Oncology, Wills Eye Hospital from November 1, 1973, to July 31, 2018, were reviewed retrospectively. The clinical features pertaining to need for ultimate enuc...
[SNA] Medani -The Sudanese Glaucoma Society is due to organize an educational workshop on Glaucoma Disease at internal conference hall in Gezira university and to be attended by numerous specialists and deputy specialists from neighboring states and in presence of members of the society in capital Khartoum.
To compare the visual functioning (VF) and vision-related QoL (VRQoL) of children aged 8-18 years treated for primary congenital glaucoma (PCG) and secondary childhood glaucoma.
Abstract Affecting nearly 80 million individuals, glaucoma is the number one cause of irreversible blindness in the world. This ocular disease describes a set of optic neuropathies of which primary open angle glaucoma (POAG) is the most common. POAG is associated with progressive visual field deterioration resulting from damage to the optic nerve and loss of retinal ganglion cells. Risk factors for POAG include elevated intraocular pressure, aging, African and Hispanic ancestry, and a positive family history of POAG. Multiple genes have been found to contribute to POAG. Much of POAG genetics and pathology has yet ...