Validation of an Objective Keratoconus Detection System Implemented in a Scheimpflug Tomographer and Comparison With Other Methods

Conclusions: KA is effective at detecting early keratoconus and agrees with trained clinical judgment. As keratoconus detection depends on the method used, we recommend using multiple methods side by side.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research

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ConclusionsTo the best of our knowledge, this is the first report to describe corneal ectasia in a patient with keratoconus following phacoemulsification surgery. Cataract surgeons should provide extra caution to patients with keratoconus and take into consideration this rare but potentially sight-threatening complication.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Conditions:   Keratoconus;   Pellucid Marginal Corneal Degeneration;   Corneal Ectasia Intervention:   Combination Product: PXL-330 Platinum device for crosslinking with Peschke riboflavin solution Sponsor:   Goodman Eye Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Keratoconus Intervention:   Other: opthalmologic examination Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
To compare accelerated collagen crosslinking (CXL) alone, CXL with simultaneous intrastromal corneal ring segments (CXL-ICR), and CXL with simultaneous topography-guided photorefractive keratectomy (CXL-TG-PRK) in progressive keratoconus, pellucid marginal degeneration (PMD) or laser in-situ keratomileusis (LASIK)-induced ectasia.
Source: Journal of Cataract and Refractive Surgery - Category: Opthalmology Authors: Source Type: research
Abstract PURPOSE: The aim of this study was to evaluate the 2-year results of epithelium-off pulsed-light accelerated corneal collagen crosslinking treatment in progressive keratoconus using 30 mW/cm2 ultraviolet A light for 6 min with a total dose of 5.4 J/cm2. METHODS: A total of 30 eyes of 22 patients with documented progressive keratoconus and treated with epithelium-off pulsed-light accelerated corneal collagen crosslinking using the KXL® crosslinking device (Avedro Inc, Waltham, MA, USA) were included in this retrospective study. Corneal tomographic measurements and best spectac...
Source: European Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Eur J Ophthalmol Source Type: research
sta D Abstract PURPOSE: The purpose was to compare the visual, refractive and aberrometric results of intrastromal corneal ring segments implantation with manual dissection and femtosecond laser-assisted surgery. METHODS: This is a multicentre study, which included consecutive patients with paracentral keratoconus, in which the difference between the axes of the topographic flattest and the coma aberration was
Source: European Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Eur J Ophthalmol Source Type: research
Purpose: To report the clinical properties and risk factors for corneal Descemet membrane (DM) folds after deep anterior lamellar keratoplasty (DALK) in patients with keratoconus. Methods: This is a retrospective case–control study. Study participants—experimental group: 44 eyes with DM folds after DALK; control group: 135 eyes without DM folds after DALK. Results: Forty eyes with DM folds were displayed as 1 or 2 translucent lines in the DM layer. Three eyes appeared as several arcuate shape lines, and 1 eye presented as a radial shape. DM folds impaired corrected visual acuity after DALK (P = 0.018). ...
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Purpose: To report visual, refractive, and corneal aberrations after implantation of a new asymmetric intracorneal ring segment (ICRS). Methods: This was a prospective, multicenter clinical study including 30 eyes of 26 patients with keratoconus. All cases were implanted with an ICRS, named the VISUMRING (VR), which had an arc length of 353 degrees and 2 asymmetric sections that can be customized in base width, length, and thickness. Ophthalmic evaluation included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refraction, topography, and anterior corneal aberrations using the Siriu...
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Purpose: To evaluate the efficacy, predictability, and safety of combined corneal collagen cross-linking (CXL), intracorneal ring segment (ICRS) implantation, and superficial phototherapeutic keratectomy (PTK) in patients with keratoconus. Methods: Fifty-five eyes received ICRS implantation, followed by CXL and PTK combination treatment. Patients were followed up for 6 months. Primary outcomes included Logarithm of the Minimum Angle of Resolution (LogMAR) uncorrected distance VA (UDVA) and corrected distance VA (CDVA), sphere, cylinder, mean spherical equivalent, index of surface variance, index of vertical asymmetry,...
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Abstract Purpose: To analyze the keratectasia area (KEA) shown in corneal topography before and after corneal cross-linking (CXL) in patients with progressive keratoconus (KC) and figure out whether KEA is appropriate for evaluating the effect of CXL. Methods: A retrospective analysis was conducted in 34 eyes from 24 progressive KC patients who have underwent CXL from 2015 to 2017. Area with K-value more than 47D shown in the corneal topography was marked and identified as KEA. Keratometry (K1, K2, and Kmax), KEA, thinnest corneal thickness (TCT), and endothelial cell density (ECD) were evaluated preoperative...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
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