Association of NUDT15 c.415C & gt;T allele and thiopurine-induced leukocytopenia in Asians: a systematic review and meta-analysis

ConclusionThe results of this meta-analysis confirm thatNUDT15 c.415C>T may be an important predictor of thiopurine-induced leukocytopenia in Asians. Genotype targeting ofNUDT15 c.415C>T before initiating thiopurine treatment may be useful to limit leukocytopenia.
Source: Irish Journal of Medical Science - Category: Journals (General) Source Type: research