Oxidant and anti-oxidant status in common brain tumors: Correlation to TP53 and human biliverdin reductase

In neurological oncology surgery practice, meningiomas as extra-axial and gliomas as intra-axial tumors are the most common brain tumors and despite modern treatment modalities, we are still far from the total cure, especially in high-grade gliomas (HGG) and again in high-grade meningiomas. Even in low-grade gliomas (LGG), recurrence or up-grading is encountered within 5 –7 years following the first surgery, although total removal has been achieved. Low-grade meningiomas such as grade-I, has also recurrence rate which is very low but possible.

Source: Clinical Neurology and Neurosurgery - May 3, 2017 Category: Neurosurgery Authors: Pinar Atukeren, Sena Oner, Oguz Baran, Rahsan Kemerdere, Bulent Eren, Ufuk Cakatay, Taner Tanriverdi Source Type: research