Chemical constituents of the root bark of Erythrina droogmansiana

Publication date: June 2017 Source:Phytochemistry Letters, Volume 20 Author(s): Kibrom Gebreheiwot Bedane, Souvik Kusari, Anke Bullach, Ishmael B. Masesane, Shetonde O. Mihigo, Michael Spiteller, Runner R.T. Majinda Two new compounds namely 7,4′-dihydroxy-2′-methoxy-3′-(3-methylbut-2-enyl)isoflavanone (1) and 5,7,3′-trihydroxy-8-(3-methylbut-2-enyl)-[6′′,6′′-dimethylpyrano(2′′,3′′:4′,5′)]isoflavone (4) were isolated from the root bark of Erythrina droogmansiana together with eight known compounds. Their structures were elucidated on the basis of spectroscopic analyses (1D- and 2D-NMR and ESI-HRMS) and by comparison with literature data. In addition, the correct 13C NMR of 5,7,2′,4′-tertahydroxy-8,5′-di-(3-metylbut-2-enyl)isoflavone (6) was assigned. The DPPH free radical scavenging properties of the isolated compounds were evaluated. Compounds 4–7 showed weak to moderate DPPH free radical scavenging activities. Graphical abstract

Source: Phytochemistry Letters - May 3, 2017 Category: Chemistry Source Type: research