Mysterious molecule's function in skin cancer identified

(Sanford-Burnham Prebys Medical Discovery Institute) SBP researcher Ranjan Perera uncovered the M.O. of a mysterious molecule called SPRIGHTLY that acts as a hub for cancer-related genes in the nucleus. The study identified 'major' RNA binding partners -- genes already implicated in a variety of cancers. In a mouse model of melanoma, tumors with reduced SPRIGHTLY grew more slowly, indicating use as a therapeutic target or biomarker.
Source: EurekAlert! - Biology - Category: Biology Source Type: news