Ceylonins G –I: spongian diterpenes from the marine sponge Spongia ceylonensis

AbstractThree new spongian diterpenes, ceylonins G –I (1–3), were isolated from the marine spongeSpongia ceylonensis collected in Indonesia, together with five known spongian diterpenes (4–8). Only4 inhibited USP7 with an IC50 value of 8.2  μM.
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research