TGen and UNC Lineberger studies help shed light on aggressive brain cancer

(The Translational Genomics Research Institute) One study showed that mutations affect how cancer starts in glial cells -- brain cells that provide support and insulation for neurons -- and how those mutations affect the way cancer evolves from low-grade gliomas to full-blown high-grade glioblastomas, the most common and deadly of primary brain cancer.The other study showed how using a combination of drugs at increased potency could prove an effective therapy against glioblastoma by inhibiting the PI3K and MAPK cellular pathways.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news