Abstract A40: Profile of DNA repair status in a recently established panel of patient-derived ovarian carcinoma xenografts
Conclusions: These data suggest the mRNA expression levels of targeted DNA repair pathway-related genes as PALB2, XPF and CDK12 predict the response to a platinum based therapy in ovarian cancer, even if they need to be prospectively validated in cohort of ovarian cancer patients.Citation Format: Federica Guffanti, Maddalena Fratelli, Monica Ganzinelli, Francesca Ricci, Maria Rosa Cappelletti, Damiele Generali, Francesca Bizzaro, Raffaella Giavazzi, Giovanna Damia. Profile of DNA repair status in a recently established panel of patient-derived ovarian carcinoma xenografts [abstract]. In: Proceedings of the AACR Special Conference on DNA Repair: Tumor Development and Therapeutic Response; 2016 Nov 2-5; Montreal, QC, Canada. Philadelphia (PA): AACR; Mol Cancer Res 2017;15(4_Suppl):Abstract nr A40.
Source: Molecular Cancer Research - Category: Cancer & Oncology Authors: Guffanti, F., Fratelli, M., Ganzinelli, M., Ricci, F., Cappelletti, M. R., Generali, D., Bizzaro, F., Giavazzi, R., Damia, G. Tags: Other Topics: Poster Presentations - Proffered Abstracts Source Type: research
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