Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST

This study provides novel insights into the biology of quadruple WT GIST that potentially resembles neuroendocrine tumors and should promote the development of specific therapeutic approaches. Mol Cancer Res; 15(5); 553–62. ©2017 AACR.

Source: Molecular Cancer Research - May 1, 2017 Category: Cancer & Oncology Authors: Pantaleo, M. A., Urbini, M., Indio, V., Ravegnini, G., Nannini, M., De Luca, M., Tarantino, G., Angelini, S., Gronchi, A., Vincenzi, B., Grignani, G., Colombo, C., Fumagalli, E., Gatto, L., Saponara, M., Ianni, M., Paterini, P., Santini, D., Pirini, M. G. Tags: Genomics Source Type: research