Hippocampal hypometabolism in older adults with memory complaints and increased amyloid burden

Conclusions:
These data show the relevant role of posterior and anterior midline regions in SMCs in older individuals. Decreased hippocampal metabolism may be a specific marker of subclinical changes in cognition due to amyloid pathology. However, longitudinal studies are needed to determine whether our findings foreshadow clinical decline.

Source: Neurology - May 1, 2017 Category: Neurology Authors: Vannini, P., Hanseeuw, B., Munro, C. E., Amariglio, R. E., Marshall, G. A., Rentz, D. M., Pascual-Leone, A., Johnson, K. A., Sperling, R. A. Tags: PET, Alzheimer's disease, Cognitive aging ARTICLE Source Type: research