Randomized controlled trials in mild cognitive impairment: Sources of variability

Conclusions: In spite of apparently similar criteria for MCI being adopted by the 7 studies, the implementation of the criteria varied a great deal. Several explanations including instruments used to characterize participants and variability among study populations contributed to the findings.

http://www.neurology.org/cgi/content/short/88/18/1751?rss=1

Source: Neurology - May 1, 2017 Category: Neurology Authors: Petersen, R. C., Thomas, R. G., Aisen, P. S., Mohs, R. C., Carrillo, M. C., Albert, M. S., For the Alzheimer's Disease Neuroimaging Initiative (ADNI) and Foundation for NIH (FNIH) Biomarkers Consortium AD MCI Placebo Data Analysis Project Team Tags: All Clinical trials, Clinical trials Methodology/study design, Alzheimer's disease, MCI (mild cognitive impairment) ARTICLE Source Type: research