Monophasic demyelination reduces brain growth in children
Conclusions:
Brain volume, and more importantly age-expected brain growth, is negatively affected by acquired demyelination, even in the absence of chronicity, implicating factors other than active inflammation as operative in this process.
Source: Neurology - Category: Neurology Authors: Aubert-Broche, B., Weier, K., Longoni, G., Fonov, V. S., Bar-Or, A., Marrie, R. A., Yeh, E. A., Narayanan, S., Arnold, D. L., Verhey, L. H., Banwell, B., Collins, D. L., On behalf of the Canadian Pediatric Demyelinating Disease Network Tags: Volumetric MRI, All Pediatric, Optic neuritis; see Neuro-ophthalmology/Optic Nerve, Acute disseminated encephalomyelitis, Transverse myelitis ARTICLE Source Type: research