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Milestones made possible #becauseofadonor

There are more than 80 children currently waiting for life-saving organ transplants at Boston Children’s Hospital. The Pediatric Transplant Center team is grateful for the donors who give these kids a second chance. Meet Maggie. The 20-year-old received her first double-lung transplant at 4 years old and her second at 7 years old. #becauseofadonor, Maggie is able to go to college. Meet Tom. At 15 years old, he received a liver transplant. #becauseofadonor, Tom, now 22, is able to run the Boston Marathon. Meet Aaron. The 10-year-old received his heart transplant at just 1 year old. #becauseofadonor, Aaron was able to get his black belt in karate. Tell us about your milestone made possible #becauseofadonor. The post Milestones made possible #becauseofadonor appeared first on Thriving Blog.
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Our Patients’ Stories Donate life double lung transplant heart transplant Heart transplant program Liver transplant Liver Transplant Program Lung Transplant Program National Donate Life Month organ donation Pediatric Transplant Cente Source Type: news

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In conclusion, a debate exists on whether aging is a disease in itself. Some authors suggest that physiological aging (or senescence) is not really distinguishable from pathology, while others argue that aging is different from age-related diseases and other pathologies. It is interesting to stress that the answer to this question has important theoretical and practical consequences, taking into account that various strategies capable of setting back the aging clock are emerging. The most relevant consequence is that, if we agree that aging is equal to disease, all human beings have to be considered as patients to be treat...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The week of April 23-27 has been designated as National Pediatric Transplant Week.  This week is to bring attention to the great need for organ donations and to honor  donors and their families whose incredibly selfless gift has given someone the gift of life.While most of us will never experience the need for a transplant, there are many of us who know someone who has a debilitating condition such as kidney dialysis that are in need of a transplant.Right now there are almost 2,000 children on the national transplant list.  Those needing hearts, lungs, eyes, tissue, liver, kidney, or some other body part are...
Source: Pediatric Health Associates - Category: Pediatrics Tags: Volunteer Opportunities Source Type: news
This study demonstrates that small peptide domains derived from native protein amelogenin can be utilized to construct a mineral layer on damaged human enamel in vitro. Six groups were prepared to carry out remineralization on artificially created lesions on enamel: (1) no treatment, (2) Ca2+ and PO43- only, (3) 1100 ppm fluoride (F), (4) 20 000 ppm F, (5) 1100 ppm F and peptide, and (6) peptide alone. While the 1100 ppm F sample (indicative of common F content of toothpaste for homecare) did not deliver F to the thinly deposited mineral layer, high F test sample (indicative of clinical varnish treatment) formed mainly C...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
ANDOVER, Mass., April 12, 2018 -- (Healthcare Sales &Marketing Network) -- TransMedics, Inc., a medical technology company that is transforming the important therapy of solid organ transplantation for patients with end-stage lung, heart and liver failure... Devices, Surgery, FDA TransMedics, Organ Care System, lung transplant, organ transplant
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
TransMedics said today that it won pre-market approval from the FDA for its OCD Lung transplant system, which is designed to keep donated human lungs in near-living condition until transplantation. The March 22 approval covers standard double-lung transplantation procedures, Andover, Mass.-based TransMedics said. The federal safety watchdog granted the PMA based on data from the 316-patient Inspire trial, the results from which were published this week in The Lancet Respiratory Medicine, comparing OCS lung with the standard of care – cold flush and storage. Inspire met its primary outcome – a composite of ...
Source: Mass Device - Category: Medical Devices Authors: Tags: Clinical Trials Regulatory/Compliance Respiratory Transplants Wall Street Beat transmedics Source Type: news
Renal ischemia-reperfusion injury (IRI) is an inherent process to kidney transplantation. The subsequent release of pro-inflammatory cytokines (e.g., IL-1 β, TNF-α, IL-6) may induce a systemic inflammatory response, resulting in pro-inflammatory cells recruitment and remote organ damage. Several studies have already documented dysfunction of the lung, heart, liver, and brain following renal IRI. The heme oxygenase-1 (HO-1), a stress-responsive enzym e endowed with cytoprotective, antiapoptotic, and immunomodulatory properties, protects kidney from renal IRI when pharmacology induced before ischemia.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Transplantation & Vascular Surgery: Renal Transplantation Vascular Surgery I Source Type: research
Transplant candidates have advanced chronic disease, which often leads to muscular and respiratory impairment contributing to reduced quality of life and daily life activities, and these patients are therefore referred to physiotherapy service. Because of this, it is necessary to know the epidemiologic and functional profile for a better physiotherapeutic approach. Inpatients of kidney, liver, heart, lung and multivisceral transplantation programs were followed up for 1 year. A comparative analysis between groups was performed, taking into account hospital stay time and functional independence measure (FIM).
Source: Transplantation Proceedings - Category: Transplant Surgery Authors: Tags: 15th Brazilian Transplantation Congress and 16th Portuguese-Brazilian Transplantation Congress Source Type: research
In this study we investigated regulatory t cells after combined lung and liver transplantation, or after isolated lung transplantation, in cystic fibrosis patients and correlated the findings with long term outcomes
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
The Model for end-stage liver disease (MELD) score, derived based on serum creatinine, bilirubin, and INR, was developed to accurately predict the probability of waitlist mortality in patients awaiting a liver transplant. Subsequently, a MELD excluding INR (MELD-XI) score was adapted to predict mortality after heart transplant (HT). Our objective was to devise a new combined scoring model (defined as CMELD-XI, derived by adding the MELD-XI score with independent predictors of 1-year mortality) to accurately predict mortality after pediatric HT (PHT).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Heart failure with reduced ejection fraction (HFrEF) following orthotopic liver transplantation (OLT) is a poorly understood phenomenon, reported in 3 to 7% of transplanted patients. The purpose of this study was to identify risk factors that may predict HFrEF following OLT.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
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