Unbound monomers do diffuse through the dentin barrier

The use of resin-based dental restorative materials is extensive in contemporary dentistry. However, significant concerns remain regarding their biocompatibility. Several studies dealing with the molecular toxicity of substances released by these biomaterials, have shown that these leachable components can cause significant cytotoxic and genotoxic effects, leading to irreversible disturbance of basic cellular functions, causing a wide variety of adverse biological reactions, including local and systemic toxicity, pulp reactions, allergic and estrogenic effects [1].
Source: Dental Materials - Category: Materials Science Authors: Source Type: research