Osteopontin RNA aptamer can prevent and reverse pressure overload-induced heart failure

Conclusion</div>Taken together, these data demonstrate that tuning down cardiac OPN signalling by an OPN RNA aptamer is a novel and effective approach for preventing cardiac hypertrophy and fibrosis, improving cardiac function, and reversing pressure overload-induced heart failure.</span>
Source: Cardiovascular Research - Category: Cardiology Source Type: research