Weak link between grandmums' smoking and autistic grandkids

Conclusion This study aimed to see whether smoking in pregnancy is linked with some traits of ASD in the smoker's grandchildren. Although this was based on a large cohort of children, the results give quite a confusing and inconclusive picture. To be frank, the study raised more questions than it answered. Maternal grandmother smoking was linked with ASD traits only in girls (in whom ASD is less common in any case) – and then only if their own mother did not smoke. When looking at actual diagnosed cases of autism, the link was only found in boys. The study had some important limitations to consider: Most of the data was on behavioural traits, not actual diagnosed ASD, which cannot necessarily be directly linked with autism diagnoses. The causes of ASD aren't known. Although the researchers attempted to adjust for some confounding variables, many other environmental and lifestyle factors could be having an influence, such as the child's or their own parent's diet, exercise or other social influences. ASD traits and autism diagnoses were only found when their own mother had not smoked in pregnancy – which indicates that it might not be smoke exposure that directly increases risk of ASD. The results rely on reports from parents on their own parents, which may have been subject to recall bias if they could not remember all the facts. Some may not have known with certainty if their own parents had smoked during pregnancy. Although it was a large sample, ...
Source: NHS News Feed - Category: Consumer Health News Tags: Pregnancy/child Neurology Mental health Genetics/stem cells Source Type: news

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Abstract The transcription factor DMRT1 (doublesex and mab-3 related transcription factor) has two distinct functions, somatic-cell masculinization and germ-cell development in some vertebrate species, including mouse and the African clawed frog Xenopus laevis. However, its transcriptional regulation remains unclear. We tried to identify DMRT1-interacting proteins from X. laevis testes by immunoprecipitation with an anti-DMRT1 antibody and MS/MS analysis, and selected three proteins, including PACT/PRKRA (Interferon-inducible double-stranded RNA dependent protein kinase activator A) derived from testes. Next, we examined t...
Source: Genetics and Molecular Biology - Category: Genetics & Stem Cells Source Type: research
CONCLUSION Infrastructural adequacy of PHCC was associated with less PCSC hospitalizations, while availability medical professional and medications were associated with higher PCSC hospitalizations.
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
ABSTRACT Objective: to know how mothers affected by the Zika virus during pregnancy became aware on the diagnosis of Congenital Zika Virus Syndrome in their child and to understand the way in which the communication of the diagnosis was transmitted. Method: a qualitative approach study, with interpretative research, based on the Resilience, Stress, Adjustment and Family Adaptation Model. The research was conducted in a Specialized Rehabilitation Center in a city of Para íba (Brazil), from June to November 2017, with 40 mothers of children with congenital Zika virus syndrome. The empirical material was produced from ...
Source: Texto e Contexto - Enfermagem - Category: International Medicine & Public Health Source Type: research
It has been nearly 2 years since I first wrote in this journal about reform efforts at the Substance Abuse and Mental Health Services Administration (SAMHSA). At that time, I described SAMHSA ’s plans to better serve Americans living with mental and s...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
BACKGROUND: In China, body packing as a means of transporting drugs was firstly found in Yunnan province in an area that shares a border with the Golden Triangle in late 1970s. Since then, drug trafficking cases that utilize body packing as the primary mod...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Objectives: Bupropion is an antidepressant that is commonly known to cause seizures in overdose. Because of concern for delayed onset of seizures, patients are frequently observed for prolonged periods after overdose. The primary objective is to eva...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
The authors regret that there were two typographical errors in the Results section of the abstract of the published article. Please see below for the corrected abstract in full. Background: The increasing use of pregabalin and the presence of pre...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
CONCLUSION: The most frequent pelvic floor dysfunctions (PFD) after birth were perineal pain, constipation, flatus incontinence, dyspareunia and IU respectively. It was seen that the symptomatic PFD was very common in the postpartum period. The results of the study emphasized the importance of lifestyle changes, avoiding perineal trauma during childbirth, and effective pelvic floor exercises in preventing PFD in pregnancy and postpartum. IMPACT STATEMENT: Nurses should acknowledge the importance of PFD after birth and identify the problems early period. Our study emphasizes size of the problem and improvement for PFD. ...
Source: Contemporary Nurse - Category: Nursing Tags: Contemp Nurse Source Type: research
Anand Vihar Bus Terminal, New Delhi, March 28, 2020. Credit: IMPRIBy Dr. Balwant Singh Mehta, Dr. Simi Mehta and Dr. Arjun KumarNEW DELHI, Mar 30 2020 (IPS) The worldwide spread of novel coronavirus disease (COVID-19) is severely affecting the global economy and as per the recent updates almost one-third to half of the global population are now under some form of a lockdown. This has threatened an economic bloodbath, where practically all economic activities around the world are witnessing a closure. According to the International Labour Organization, nearly 25 million jobs could be lost worldwide due to the pandemic and ...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Featured Global Headlines Health Human Rights TerraViva United Nations OPINION/NGO Source Type: news
Abstract The study was conducted to evaluate effects of intrauterine administration of proteolytic enzymes on endometrial inflammation and reproductive performance in postpartum water buffalo cows with subclinical endometritis (SCE). Cows (n = 38) with SCE (≥ 18 % PMN i.e.; polymorphonuclear cells) on day 21 postpartum (21 dpp), were allocated into treatment (TR; n = 19; intrauterine infusion of trypsin, chymotrypsin and papain in 20 ml normal saline on 21 dpp) and control (PC; n = 19; intrauterine administration 20 ml saline) groups. Cows without SCE (
Source: Animal Reproduction Science - Category: Zoology Authors: Tags: Anim Reprod Sci Source Type: research
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