Restless legs syndrome and cardiovascular diseases: A case-control study

ConclusionDespite some limitations in the design of this study, we found that most of the treated patients for primary RLS had no association with CVD and hypertension after controlling for key potential confounders. Comorbid CVD or hypertension was associated with cardiovascular risk factors, but not with RLS features except for older age at onset.
Source: PLoS One - Category: Biomedical Science Authors: Source Type: research

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We report that Tbx5 and Gata4 interact with opposite signs for atrial rhythm controls compared with cardiac development. Using mouse genetics, we found that AF pathophysiology caused by Tbx5 haploinsufficiency, including atrial arrhythmia susceptibility, prolonged action potential duration, and ectopic cardiomyocyte depolarizations, were all rescued by Gata4 haploinsufficiency. In contrast, Nkx2-5 haploinsufficiency showed no combinatorial effect. The molecular basis of the TBX5/GATA4 interaction included normalization of intra-cardiomyocyte calcium flux and expression of calcium channel genes Atp2a2 and Ryr2. Furthermore,...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
RESUMO Objetivo: Avaliar as respostas fisiol ógicas e do sistema nervoso autônomo de recém-nascidos prematuros ao posicionamento do corpo e ruídos ambientais na unidade de terapia intensiva neonatal. Métodos: Este foi um estudo quasi-experimental. O sistema nervoso autônomo de recém-nascidos foi avaliado com base na variabilidade da fr equência cardíaca quando os recém-nascidos foram expostos ao ruído ambiental e colocados em diferentes posições: supina sem suporte, supina com restrição manual e prona. Resultados: Cinquent...
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
Conclusion: Septic patients with a past history of heart failure received 1L less IV fluids in the first 24 hours with no difference in mortality.
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
RESUMO A sepse persiste como importante sobrecarga à saúde pública nos Estados Unidos e em todo o mundo. Com o crescente uso de tecnologias laboratoriais, tem se renovado o interesse na utilização de biomarcadores na sepse, para auxiliar em um processo mais preciso e direcionado para tomadas de decisão. Os peptídeos natriuréticos vem sendo c ada vez mais reconhecidos por seu papel que vai além da insuficiência cardíaca. Estes peptídeos estão comumente elevados em pacientes críticos que apresentam condições de disf...
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
The objective of this literature review is to present the theoretical and practical aspects of extracorporeal membrane oxygenation support for respiratory and/or cardiac functions in critically ill patients.
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
Suicide is one of the major causes of death in young people, in whom suicide can occur in clusters. In this Review, we have investigated definitions and epidemiology of such clusters, the factors associated with them, mechanisms by which they occur, and me...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Leading suicide theories and research in adults suggest that pain can exacerbate the suicidal risk of an individual. Although pain and suicidality (including suicidal ideation, behaviour, and death by suicide) both increase in prevalence during adolescence...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
To examine differences in life satisfaction, sleep, and fatigue after hysterectomy among women with preoperative pelvic pain and/or depression.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Virtual Poster Session 3: Endometriosis (9:50 AM – 10:00 AM) 9:50 AM: STATION S Source Type: research
The goal of this pilot study is to explore the relationship between sleep and pain in endometriosis patients undergoing laparoscopic surgery using novel radio-wave sensing technology.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Open Communications 26:  Endometriosis (4:10 PM – 5:15 PM) 4:17 PM Source Type: research
Preoperative depression has been linked to adverse outcomes following hysterectomy, including increased acute and chronic postoperative pain. The goal of this study was to determine whether preoperative depression is associated with increased opioid use following hysterectomy.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Open Communications 18:  Endometriosis (2:15 PM – 3:00 PM) 2:29 PM Source Type: research
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