American Gastroenterological Association Institute Technical Review on the Role of Elastography in Chronic Liver Diseases

Chronic liver diseases (CLDs), due to chronic hepatitis  C; hepatitis B; nonalcoholic fatty liver diseases (NAFLD); and alcoholic liver disease, are a leading cause of morbidity and mortality globally. Early identification of patients with cirrhosis at high risk of progression to liver-related complications may facilitate timely care and improve outcome s. With risks and misclassification associated with invasive tests, such as liver biopsy, noninvasive imaging modalities for liver fibrosis assessment have gained popularity.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: AGA Section Source Type: research

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Publication date: Available online 24 January 2020Source: Journal of Vascular and Interventional RadiologyAuthor(s): Yumei Yang, Yanfang Zhang, Yumin Wu, Jibing Chen, Bing Liang, Quanhong Chen, Qiuyu Wang, Jialing Lyu, Yong Li, Feng Mu, Duanming DuAbstractPurposeTo evaluate the efficacy and safety of percutaneous argon-helium cryoablation (CA) for hepatocellular carcinoma (HCC) abutting the diaphragm (
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
Publication date: Available online 24 January 2020Source: Microbial PathogenesisAuthor(s): Mani Divya, Marimuthu Govindarajan, Sivashanmugam Karthikeyan, Elumalai Preetham, Naiyf S. Alharbi, Shine Kadaikunnan, Jamal M. Khaled, Taghreed N. Almanaa, Baskaralingam VaseeharanAbstractβ-Glucan-binding protein (βGBP) is important for the rational expansion of molecular biology. Here, zinc oxide nanoparticle (ZnONP) was synthesized using βGBP from the crab Scylla serrata (Ss-βGBP-ZnONP). Ss-βGBP-ZnONP was observed as a 100 kDa band on sodium dodecyl sulfate polyacrylamide gel and characterized with UV&nd...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
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Source: Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
CONCLUSION: In this study, we demonstrated that silibinin as an anti-inflammatory therapy is a potential alternative to manage obesity, as well as its related complications. Moreover, silibinin-based therapies could further evolve as a novel treatment to manage various inflammation-driven disorders. PMID: 31973745 [PubMed - in process]
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research
Source: Digestive and Liver Disease - Category: Gastroenterology Source Type: research
Publication date: April 2020Source: Biomedicine &Pharmacotherapy, Volume 124Author(s): Hongshan Li, Yingfei Xi, Xin Xin, Huajie Tian, Yiyang HuAbstractBackgroundOur previous studies found that salidroside can effectively treat non-alcoholic steatohepatitis (NASH). Here, we discuss the mechanism of salidroside in the treatment of NASH with a focus on the gut microbiota-bile acid-farnesoid X receptor axis.MethodsA NASH mouse model was created by providing mice with a high-fat diet (HFD) for 14 weeks. Mice were randomly divided into the HFD group, HFD + salidroside treatment group, and HFD + ob...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 25 January 2020Source: Materials Today: ProceedingsAuthor(s): V. Vinayaka Ram, Rhythm Singhal, R. ParameshwaranAbstractThe growing energy demand and energy requirements in the construction sector have paved way to the development and incorporation of the energy efficient materials and technologies in building envelopes. This research work is aimed at investigating the suitability of a pumpable cement concrete with nanomaterials embedded phase change material (PCN-PCM) for achieving energy efficiency in buildings through passive cooling application. In this work, an attempt was made to mix...
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
Publication date: June 2020Source: Materials Today Communications, Volume 23Author(s): Jomy Joseph, Abhishek Sharma, Baidehish Sahoo, Jinu Paul, Ajay M. SidparaAbstractPoly (vinyl alcohol) (PVA)/ multi-layered graphene (MLG) / multi-walled carbon nanotubes (MWCNT) nanocomposites of different compositions were made through the solution casting method. Filler loadings used were 20 wt. % MLG, 17.5 wt.% MLG / 2.5 wt.% MLG, 15 wt.% MLG / 5 wt.% MWCNT and 10 wt.% MLG / 10 wt.% MWCNT. Mechanical strength of the composites was evaluated by testing their tensile and viscoelastic properties. Differential thermal analys...
Source: Materials Today Communications - Category: Materials Science Source Type: research
ConclusionMDD seems to be highly prevalent, underdiagnosed and undertreated in BD and SZ homeless subjects. Beyond antidepressants, add-on strategies including complementary agents, lithium, lamotrigine/carbamazepine or anti-inflammatory drugs and the specific care of alcohol and substance use disorders may be recommended to improve the prognosis of this specific population in addition to other interventions including housing and resocialization. Violent victimization is also frequent and should be specifically prevented in this vulnerable population.
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Conclusions: In this initial small series, we found that robot-assisted VVF repair is a safe procedure with results comparable to transvaginal repair. This procedure has a high success rate and few complications without using interposed tissue. PMID: 31975648 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Urology - Category: Urology & Nephrology Tags: Scand J Urol Source Type: research
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