Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy

Conclusions
We identified and replicated a genetic association at 22q12.2 with tonsillectomy. Further functional investigation is required to illuminate whether the molecular mechanisms underlying the genetic association involve general lymphoid hyper-reaction throughout the mucosa-associated lymphoid tissue system.

Source: Journal of Medical Genetics - April 24, 2017 Category: Genetics & Stem Cells Authors: Feenstra, B., Bager, P., Liu, X., Hjalgrim, H., Nohr, E. A., Hougaard, D. M., Geller, F., Melbye, M. Tags: Genome-wide studies Source Type: research