Angiotensin II Peptide Vaccine Protects Ischemic Brain Through Reducing Oxidative Stress [Basic Sciences]

Conclusions—Our findings indicate that Ang II vaccination exerts neuroprotective and antioxidative effects in cerebral ischemia, with renin–angiotensin system blockade by penetration of anti–Ang II antibodies into ischemic brain lesion. Ang II peptide vaccination could be a promising approach to treat ischemic stroke.

Source: Stroke - April 24, 2017 Category: Neurology Authors: Kouji Wakayama, Munehisa Shimamura, Jun-ichi Suzuki, Ryo Watanabe, Hiroshi Koriyama, Hiroshi Akazawa, Hironori Nakagami, Hideki Mochizuki, Mitsuaki Isobe, Ryuichi Morishita Tags: Basic Science Research, Ischemic Stroke Original Contributions Source Type: research