Increased cortical network activity in a migraine mutant mouse following traumatic brain injury (S47.004)

Conclusions:Our data suggest that CK1d mutant animals show a distinct response to TBI, consistent with an increase in network excitability, and congruent with the increased susceptibility to PTH seen in migraineurs.Study Supported by: NIH R01 NS085413, DoD CDMRP PR130373Disclosure: Dr. Service has nothing to disclose. Dr. Sawant-Pokam has nothing to disclose. Dr. Mendez has nothing to disclose. Dr. Brennan has received personal compensation for activities with MAP Pharmaceuticals and Allergan as a member of an advisory board. Dr. Brennan received research support from Electrocore LLC.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Service, C. A., Sawant-Pokam, P., Mendez, J., Brennan, K. C. Tags: Headache: Basic and Clinical Science Source Type: research