Central positional vertigo (P6.045)

Conclusions:Migraine may be a benign cause of CPV, however, a broad spectrum of diseases including tumors, stroke, infections and neurodegenerative disorders may be responsible. Earlier detection of posterior fossa lesions is critical to improve the outcome. Moreover, central positional vertigo/nystagmus could be the very first manifestation of the underlying disease.Central positional nystagmus is often an unrecognized entity. In this series, 3 patients had isolated positional DBN and truncal ataxia as the initial neurologic abnormality, one of them with a CNS neoplasm. Diagnostic clues for central localization are: presence of other neurologic signs, additional ocular motor and vestibular abnormalities, nystagmus without vertigo, atypical direction nystagmus, rapid vertigo recurrence and poor response to repositioning maneuvers. Vomiting, absence of nystagmus latency and long lasting nystagmus may be softer associations.Disclosure: Dr. De Schutter has received personal compensation for activities with Abboth as a speaker. Dr. Kattah has received personal compensation for activities with Pfizer as a consultant. Dr. Kattah has received personal compensation in an editorial capacity as an editor for E-Medicine.

Source: Neurology - April 17, 2017 Category: Neurology Authors: De Schutter, D., Kattah, J. Tags: Neuro-opthalmology/Neuro-otology II Source Type: research