The oculomotor restricted protein synaptotagmin 13 protects motor neurons from degeneration in ALS and SMA (P3.131)

Conclusions:Identification of the mechanisms of neuronal differential vulnerability may lead to development of new therapeutic strategies that prevent the progressive neurodegeneration in MN diseases.Study Supported by: Cariplo Foundation to SC (2012-0513), Thierry Latran Foundation to SC and EH, JPND; 529-2014-7500 to SC and EH; ARISLA to SC.Disclosure: Dr. Nizzardo has nothing to disclose. Dr. Rizzo has nothing to disclose. Dr. Taiana has nothing to disclose. Dr. Allodi has nothing to disclose. Dr. Aguila Benitez has nothing to disclose. Dr. Nijssen has nothing to disclose. Dr. Ulzi has nothing to disclose. Dr. Melzi has nothing to disclose. Dr. Del Bo has nothing to disclose. Dr. Bresolin has nothing to disclose. Dr. Comi has nothing to disclose. Dr. Hedlund has nothing to disclose. Dr. Corti has nothing to disclose.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Nizzardo, M., Rizzo, F., Taiana, M., Allodi, I., Benitez, J. A., Nijssen, J., Ulzi, G., Melzi, V., Del Bo, R., Bresolin, N., Comi, G., Hedlund, E., Corti, S. Tags: Neuromuscular and Clinical Neurophysiology (EMG): Motor Neuron Disease I Source Type: research