Sensitivity and specificity of three screening questions for cognitive disorders (p2.303)

Conclusions:The ESQ exhibited a poor PPV and NPV for the diagnosis of HAND. When ANI was excluded, the ESQ had a good NPV to rule out symptomatic NCD. Higher depression scores were significantly associated with positive answers to the ESQ.Disclosure: Dr. Métral has nothing to disclose. Dr. Locatelli has nothing to disclose. Dr. Kovari has nothing to disclose. Dr. Calmy has nothing to disclose. Dr. Gutbrod has nothing to disclose. Dr. Brugger has nothing to disclose. Dr. Monsch has received personal compensation for activities with Novartis and Schwabe. Dr. Monsch has received research support from Zinfandel Pharmaceuticals. Dr. Darling has nothing to disclose. Dr. Du Pasquier has received personal compensation for activities with Biogen, Novartis, Abbott, ViiV, EMD Serono, and Merck Sharp & Dohme Ltd. Dr. Cavassini has received research support from Merck Sharp & Dohme Ltd., and Gilead.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Metral, M., Locatelli, I., Kovari, H., Calmy, A., Gutbrod, K., Brugger, P., Monsch, A., Darling, K., Pasquier, R. D., Cavassini, M. Tags: HIV, HTLV-I, PML, Other Viral Infections, and CJD Source Type: research