Atrophy of spinal cord gray matter is detectable at an early stage of multiple sclerosis (S2.003)

Conclusions:SC GM atrophy is already detectable at an early stage of MS, in absence of detectable WM atrophy, and affects both the cervical and thoracic cord.Disclosure: Dr. Schlaeger has nothing to disclose. Dr. Papinutto has nothing to disclose. Dr. Zhu has nothing to disclose. Dr. Datta has nothing to disclose. Dr. Bevan has nothing to disclose. Dr. Caverzasi has nothing to disclose. Dr. Jordan has nothing to disclose. Dr. Lobach has nothing to disclose. Dr. Keshavan has nothing to disclose. Dr. Kirkish has nothing to disclose. Dr. Stern has nothing to disclose. Dr. Devereux has nothing to disclose. Dr. Baker has nothing to disclose. Dr. Bove has nothing to disclose. Dr. Gelfand has received compensation for consulting on a scientific advisory board for Genentech. He also also received compensation for medical-legal consulting. Dr. Gelfand's wife received compensation for consulting on a scientific advisory board for Eli Lilly, Zosano and travel expense reimbursement from Teva. . Research support to UCSF from Genentech for a clinical trial and Quest Diagnostics for development of a dementia care pathway. Dr. Gelfand's wife received research support to UCSF from Allergan and eNeura.. Dr. Graves has received research support from Genentech, Biogen and S3 Group. Dr. Green has received personal compensation for activities with Inception Sciences, Mylan Pharma, Medimmune, and Bionure. Dr. Green has received personal compensation for serving on the board of Inception Sciences. D...

Source: Neurology - April 17, 2017 Category: Neurology Authors: Schlaeger, R., Papinutto, N., Zhu, A., Datta, E., Bevan, C., Caverzasi, E., Jordan, K., Lobach, I., Keshavan, A., Kirkish, G., Stern, W., Devereux, M., Baker, N., Bove, R., Gelfand, J., Graves, J., Green, A., Waubant, E., Wilson, M., Goodin, D., Cree, B., Tags: Neuroimaging in MS Source Type: research