Parental family history of dementia in relation to subclinical brain disease and dementia risk

Conclusions:
Parental history of dementia increases risk of dementia, primarily when age at parental diagnosis is <80 years. Unexplained heredity may be attributed in part to cerebral hypoperfusion and small vessel disease. We found no evidence of preferential maternal compared to paternal transmission.

Source: Neurology - April 24, 2017 Category: Neurology Authors: Wolters, F. J., van der Lee, S. J., Koudstaal, P. J., van Duijn, C. M., Hofman, A., Ikram, M. K., Vernooij, M. W., Ikram, M. A. Tags: Clinical neurology history, All Cognitive Disorders/Dementia, Alzheimer's disease, All epidemiology ARTICLE Source Type: research