Upregulation of the tight junction protein occludin: effects on ventilation-induced lung injury and mechanisms of action
Conclusion:
Mechanical ventilation can activate the PKC signaling pathway and tight junction proteins participate in this pathway. Up-regulation of occludin can reduce ventilation-induced lung injury.
Source: BMC Pulmonary Medicine - Latest articles - Category: Respiratory Medicine Authors: Mengjie LiuChangping GuYuelan Wang Source Type: research